كامپوزيت چارچوب¬هاي فلزي-آلي با زئوليت‌ به عنوان جاذب استخراج فازجامد براي پيش‌تغليظ و استخراج آنتي‌اكسيدان‌ها و تعيين مقدار آن‌ها با كروماتوگرافي مايع با كارايي بالا

Composite of Metal-Organic Frameworks with Zeolite as solid-phase extraction adsorbent for pre-concentration an‎d extraction of antioxidants an‎d their determination by High Performance Liquid Chromatography

شيمي تجزيه

In the present study, dispersive μ-Solid Phase Extraction (d-μSPE) based on composite of (MIL-68-Al@Zeolite ZSM-5) was developed for the isolation an‎d preconcentration of the Antioxidant quercetin an‎d its amount was determined by high-performance liquid chromatography with a diode array detector. Metal-organic frameworks an‎d Composite MOF@Zeolite were synthesized an‎d their absorption percent toward quercetin was compared. Characterization of synthesized sorbents using Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), nitrogen gas adsorption-desorption isotherm (BET), scanning electron microscopy (SEM) an‎d energy dispersive spectroscopy (EDS) was performed. Factors affecting the quercetin extraction via d-μSPE were optimized by one variable at a time method. the quercetin extraction calibration curve was obtained Under optimal conditions. The presented method showed a linear range of 0.7-30.0 mg/L with a correlation coefficient of R2=0.9989 an‎d satisfactory recovery between 80.6-95.7%. Quercetin limits of detection an‎d quantification were 0.2 mg/L an‎d 0.6 mg/L, respectively, an‎d the precision of the proposed method with relative stan‎dard deviation (RSD) was in the range of 1.3-2.9%. This method was used to extract quercetin from black tea, green tea, coffee an‎d the results showed an acceptable performance.

3

156915