چكيده لاتين
Background and Purpose: In recent years, various combinations of nutritional supplements have attracted the attention of researchers as a way to improve athletic performance and accelerate muscle recovery processes after intense exercise. The aim of the present study was to investigate The effect of seven days of curcumin supplementation combined with piperine on plasma levels of inflammatory cytokine markers after an acute session of plyometric training in female tennis players
Materials and Methods: This study was a quasi-experimental crossover trial with three different interventions: (1) plyometric training + placebo, (2) curcumin supplementation in combination with piperine, (3) control without plyometric training + placebo. In this design, 12 healthy female elite tennis participants from Isfahan (mean and standard deviation age: 24.83±1.26 years; height: 169.58±2.31 cm; weight: 62.91±1.97 kg; body mass index: 21.87±0.52 kg/height squared in meters) were purposively selected and then randomly assigned to one of 6 intervention sequences. Each participant received all three interventions over a period of three weeks, and a 7-day washout period was included between each intervention to eliminate residual effects. The plyometric training protocol consisted of an acute training session lasting approximately 45 minutes, consisting of high knee movements, jump squats, burpees, single-leg jumps and double-leg jumps. Players in the intervention groups received 500 mg curcumin capsules and 20 mg piperine, and players in the placebo groups received one 540 mg capsule containing starch or cellulose flour for seven days with lunch and dinner. To measure serum levels of IL-6, CRP, and IL-1RA in each session, blood samples were collected from the players at three time periods (1) pre-test (fasting), (2) immediately after the intervention, and (3) 24 hours after the intervention. Repeated-measures analysis of variance with Bonferroni post-hoc test was used to analyze the data. The results were analyzed using SPSS version 23 software, and the significance level was considered to be P ≤ 0.05.
Results: The results showed that in the exercise + supplement group, inflammatory indices increased immediately after exercise, but this increase was less than in the exercise + placebo group and returned to baseline levels 24 hours after exercise; while the exercise + placebo group experienced a significant increase in inflammation both immediately and 24 hours after exercise, and the control group did not show any significant changes. Also, in the exercise + supplement group, explosive speed and power increased significantly immediately after exercise and improved 24 hours after exercise compared to previous times, but no significant change was observed in the placebo and control groups.
Conclusion: The findings show that curcumin + piperine supplementation can help improve the bodyʹs response to intense exercise by accelerating the inflammatory recovery process and preventing inflammatory markers from remaining at high levels for a long time, which can play an important role in the training and nutritional planning of elite athletes, especially female athletes.
