چكيده لاتين
In the first part of this thesis, a calixarene-based acidic ionic liquid immobilized on Fe3O4 magnetic nanoparticles coated with epoxy-functionalized silica (Calix-AIL-MN) was successfully synthesized, and characterized by various spectroscopic and analytical techniques such as
FT-IR, NMR, CHNS, ICP, TGA, VSM, SEM, EDX, elemental-mapping and TEM. This catalytic system showed excellent activity in the selective synthesis of 4-amino-1,3,4- thiadiazolo-2-yl-2H-chromen-2-ones and 6H,7H-chromeno[4,3-d][1,3,4]thiadiazolo[3,2-a]pyrimidines through the one-pot three-component reaction of 4-aminocoumarin, aldehydes, and 2-amino-1,3,4-thiadiazoles under thermal conditions and microwave irradiation, respectively.
In the second part of this research, the ionic liquid catalyst, tetra-tert-butylcalix[4]arene triphenylphosphonium tribromo cuprate (Calix-IL@CuBr3) was prepared and characterized by various spectroscopic and analytical techniques such as FT-IR, NMR, ICP, TGAand XPS analysis. The Calix-IL@CuBr3 was used as an efficient catalyst for the preparation of new derivatives of 4H-pyrano[2,3-d]pyrimidine-4-ones through a multicomponent reaction between 1,3-diphenyl-2-thiobarbituric acid, aldehyde and phenyl acetylene.
Short reaction times, high yields, easy recovery and reuse of the catalyst, and solvent-free conditions are the most prominent features of these methods, which make them as green and sustainable processes for the synthesis of these very important fused heterocycles.
