3752

edited by Rafael Maldonado

Humana Press

c2003

x, 346 p. ill.

Includes bibliographical references and index , Machine generated contents note: PART I. OPIOID ADDICTION -- 1 Molecular Mechanisms of Opioid Dependence by Using Knockout Mice -- Brigitte L. Kieffer and Frederic Simonin -- 2 Molecular Genetic Approaches -- Theo Mantamadiotis, Giinther Schiitz, and Rafael Maldonado -- 3 Opiate Addiction: Role of the cAMP Pathway and CREB -- Lisa M. Monteggia and Eric J. Nestler -- 4 Different Intracellular Signaling Systems Involved in Opioid Tolerance/Dependence -- Thomas Koch, Stefan Schulz, and Volker Hillt -- 5 Inhibitors of Enkephalin Catabolism: New Therapeutic Tool in Opioid Dependence -- Florence Noble and Bernard P. Roques --PART II. PSYCHOSTIMULANT ADDICTION -- 6 Recent Advances in the Molecular Mechanisms of Psychostimulant Abuse Using Knockout Mice -- Cecile Spielewoy and Bruno Giros -- 7 Opioid Modulation of Psychomotor Stimulant Effects -- Toni S. Shippenberg and Vladimir I. Chefer -- 8 Influence of Environmental and Hormonal Factors in Sensitivity to Psychostimulants -- Michela Marinelli and Pier Vincenzo Piazza -- 9 Development and Expression of Behavioral Sensitization: Temporal Profile of Changes in Gene Expression -- Peter W. Kalivas --PART III. CANNABINOID ADDICTION -- 10 New Advances in the Identification and Physiological Roles of the Components of the Endogenous Cannabinoid System -- Ester Fride and Raphael Mechoulam -- 11 Integration of Molecular and Behavioral Approaches to Evaluate Cannabinoid Dependence -- Dana E. Selley, Aron H. Lichtman, and Billy R. Martin -- 12 Opioid System Involvement in Cannabinoid Tolerance and Dependence -- Rafael Maldonado --PART IV. ALCOHOL AND NICOTINE ADDICTION -- 13 Current Strategies for Identifying Genes for Alcohol Sensitivity -- John C. Crabbe -- 14 Genetic Basis of Ethanol Reward -- Christopher L. Cunningham and Tamara J. Phillips -- 15 Behavioral and Molecular Aspects -- of Alcohol Craving and Relapse -- Rainer Spanagel -- 16 Molecular and Behavioral Aspects of Nicotine Dependence and Reward -- Emilio Merlo Pich, Christian Heidbreder, Manolo Mugnaini, -- and Vincenzo Teneggi.

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616

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