1889

[edited by] Roya Khosravi-Far, Eileen White

Springer

c2008

xiv, 356 p. ill

Advances in experimental medicine and biology

Includes bibliographical references and index , Cell death : history and future / Zahra Zakeri and Richard A. Lockshin -- Caspase mechanisms / Guy S. Salvesen and Stefan J. Riedl -- The mitochondrial death pathway / Anas Chalah and Roya Khosravi-Far -- Apoptotic pathways in tumor progression and therapy / Armelle Melet ... [et al.] -- Therapeutic targeting of death pathways in cancer : mechanisms for activating cell death in cancer cells / Ting-Ting Tan and Eileen White -- Overcoming resistance to apoptosis in cnacer therapy / Peter Hersey, Xu Dong Zhang, and Nizar Mhaidat -- Trail receptors : targets for cancer therapy / Robin C. Humphreys and Wendy Halpern -- Rational design of therapeutics targeting the BCL-2 family : are some cancer cells primed for death but waiting for a final push? / Victoria Del Gaizo Moore and Anthony Letai -- Autophagy and tumor suppression : recent advancesin understanding the link between autophagic cell death pathways and tumor development / Shani Bialik and Adi Kimchi -- Regulation of programmed cell death by the P53 pathway / Kageaki Kuribayashi and Wafik S. El-Deiry -- Regulation of programmed cell death by NF-[kappa]B and its role in tumorigenesis and therapy / Yongjun Fan ... [et al.] -- Targeting proteasomes as therapy in multiple myeloma / Dharminer Chauhan, Teru Hideshima, and Kenneth C. Anderson -- Histone deacetylase inhibitors : mechanisms and clinical significance in cancer : HDAC inhibitor-induced apoptosis / Sharmila Shankar and Rakesh K. Srivastava -- RNA interference and cancer : endogenous pathways and therapeutic approaches / Derek M. Dykxhoorn, Dipanjan Chowdhury, and Judy Lieberman -- Cancer stem cells and impaired apoptosis / Zainab Jagani and Roya Khosravi-Far.

Khosravi-Far, Roya. , White, Eileen

571.

936

P964

978-1-4020-6554-5