• RecordNumber
    127
  • Title

    Molecular neurosurgery with targeted toxins

  • Author Statement
    edited by Ronald G. Wiley and Douglas A. Lappi
  • Publication
    Humana Press
  • Publication Year
    c2005
  • Collation
    xi, 311 p. : ill.
  • Notes
    Introduction to molecular neurosurgery / Ronald G. Wiley and Douglas A. Lappi -- Ribosome-inactivating proteins / Fiorenzo Stirpe -- Biochemical, physiological, and behavioral characterizations of the cholinergic basal forebrain lesion produced by 192 IgG-saporin / Jerene J. Waite -- Basal forebrain cholinergic lesion by 192 IgG-saporin: a tool to assess the consequences of cortical cholinergic dysfunction in Alzheimers disease / Reinhard Schliebs -- 192 IgG-saporin-induced partial cortical cholinergic deafferentation as a model for determining the interactions between brain aging and neurodevelopmental defects in the cortical cholinergic input system / Martin Sarter and John P. Bruno -- Exploring the role of acetylcholine in primate cognition using Me20.4 IgG-saporin / Rosalind M. Ridley and Harry F. Baker -- Cortical cholinergic deafferentation induces A-beta deposition: towards a physiologic animal model of Alzheimer’s disease / Thomas G. Beach ... [et al.] -- Chemical dissection of brain glucoregulatory circuitry / Sue Ritter ... [et al.] -- Cardiovascular deficits after lesions of C1 adrenergic neurons with a saporin-based immunotoxin / Patrice G. Guyenet, Ruth L. Stornetta, and Ann M. Schreihofer -- Saporin conjugates and pain / Ronald G. Wiley and Douglas A. Lappi -- The use of saporin conjugates to dissect neurons responsible for sleep and wakefulness / Carlos Blanco-Centurion ... [et al.] -- Isolectin I-B4-mediated cytotoxic targeting of sensory neurons / Lucy Vulchanova and Christopher N. Honda -- B fragment of cholera toxin conjugated to saporin / Peter T. O’hara, Kanwarjit Kelley, and Luc Jasmin. , Includes bibliographical references and index
  • Subject

    Neurotoxic agents --Therapeutic use , Drug targeting , Antibody-toxin conjugates --Therapeutic use , Immunotoxins --therapeutic use , Antibodies, Monoclonal --therapeutic use , Cholinergic Fibers --metabolism , Neurobiology --methods , Neurons --pathology

  • ADDED ENTRIES
    Wiley, Ronald G., 1947- , Lappi, Douglas A.
  • Main class
    616.
  • Sub class
    80471
  • Cutter no
    M718
  • ISBN
    1-58829-199-5